insomnia

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Related to Fatal familial insomnia: kuru
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Synonyms for insomnia

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an inability to sleep

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The TSE family of diseases includes bovine spongiform encephalopathy (BSE), which affects cattle; transmissible mink encephalopathy; feline spongif0rm encephalopathy; chronic wasting disease of deer and elk; and kuru, both classical and variant Creutzfeldt-Jakob disease, Gerstmann-Straussler-Scheinker syndrome, and fatal familial insomnia, five rare diseases in humans.
Abstract: Fatal familial insomnia (FFI) is an inherited disease caused by a mutation in the protein prion gene.
Fatal familial insomnia and familial Creutzfeldt-Jakob disease: disease phenotype determined by a DNA polymorphism.
The group includes BSE of cows, serapie which affect sheep and goats; transmissible mink encephalopathy (TME); feline spongiform encephalopathy; chronic wasting disease (CWD) of mule deer and rocky mountain elk; and kuru, Gerstmann-Straussler-Seheinker syndrome (GSS), fatal familial insomnia (FFI), Alpers syndrome, and Creutzfeldt-Jakob disease (CJD) of man.
The pathogenic form of prion proteins (PrPs) has been associated with fatal diseases, including mad cow disease in cattle, scrapie in sheep, and the human disorders Creutzfeldt-Jakob Disease (CJD), Gerstmann-Straussler- Scheinker, Kuru, and fatal familial insomnia.