factor VII

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Related to Factor VIIa: factor VIII, Novoseven
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  • noun

Synonyms for factor VII

a coagulation factor formed in the kidney under the influence of vitamin K

References in periodicals archive ?
The company's most advanced programme is an improved next-generation coagulation Factor VIIa variant, marzeptacog alfa (activated), that has successfully completed an intravenous Phase 1 clinical trial in individuals with severe hemophilia A or B.
Sequential therapy with activated prothrombin complex concentrate and recombinant factor VIIa in patients with severe haemophilia and inhibitors.
LFB has been producing limited amounts of Factor VIIa in the milk of rabbits in France.
Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity.
A randomized, double-blind comparison of two dosage levels of recombinant factor VIIa in the treatment of joint, muscle and mucocutaneous haemorrhages in persons with haemophilia A and B, with and without inhibitors.
The patient was started on Recombinant Factor VIIa (Novo Seven) 270mcg/kg followed by 180 mcg/kg every six hours.
Consider off-label treatment with recombinant factor VIIa only after the patient has received approximately 10 U of packed RBCs and full factor replacement.
More recently, recombinant factor VIIa has been used investigationally in individuals with a variety of hemorrhagic disorders, including neurologic bleeding.
We recently announced that GTC is focused on achieving key goals related to Factor VIIa, ATryn(R) and our 'bio-superior' product candidates.
Also in Maxygen's pipeline are a new Factor VIIa product candidate for the treatment of hemophilia and new CTLA4-Ig product candidates for the treatment of rheumatoid arthritis.
Inflammatory cytokines upregulate endothelial expression of tissue factor, the procoagulant protein required for factor VIIa activity," and down regulate endothelial expression of heparin sulfate/ glycosaminoglycans, the cofactors for the anticoagulant activity of antithrombin.
Unchanged global fibrinolytic capacity despite increased factor VIIa activity in Behcet's disease: evidence of a prethrombotic state.