Sir James Paget

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Synonyms for Sir James Paget

English pathologist who discovered the cause of trichinosis (1814-1899)

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References in periodicals archive ?
The high recurrence-free rate we have seen supports the view that Mohs surgery with cytokeratin-7 immunohistochemistry should be considered the curative treatment of choice for both primary and recurrent extramammary Paget disease of the skin.
Extramammary Paget disease expresses androgen receptor but often lacks expression of estrogen receptor and progesterone receptor.
Vulvar Toker cells: the long-awaited missing link: a proposal for an origin-based histogenetic classification of extramammary Paget disease.
The pathologic differential diagnosis of clear cell squamous cell carcinoma in situ includes extramammary Paget disease, mammary Paget disease, benign and malignant tumors characterized by intraepidermal pagetoid cells, and other clear cell neoplasms of the skin.
Pathologic differential diagnosis of clear cell squamous cell carcinoma in situ: conditions with intraepidermal Pagetoid cells Clear cell papulosis Clear cell squamous cell carcinoma in situ Clear cells of Toker (of the nipple epidermis) Extramammary Paget disease Cutaneous T-cell lymphoma Eccrine porocarcinoma Histiocytosis X (Langerhans cell histiocytosis) Langerhans cell microabscess (in cutaneous delayed hypersensitivity reactions) Malignant melanoma in situ (superficial spreading) Merkel cell carcinoma (with pagetoid intraepidermal spread) Metastasis (epidermotropic) Pagetoid dyskeratosis Paget disease (extramammary and mammary) Sebaceous carcinoma Spitz nevus (pagetoid) Table 2.
We also review reports of other patients with extramammary Paget disease who were treated with this therapy.
The cytoplasm of the atypical cells was stained with periodic acid-Schiff stain, confirming the diagnosis of extramammary Paget disease.
The large cells of extramammary Paget disease show large atypical nuclei and cytoplasmic mucin instead of the central pyknotic nuclei and mucin-negative cytoplasm characteristic of the cells seen in pagetoid dyskeratosis.
Surgery also improves PA secondary to anorectal disorders such as fissures, extramammary Paget disease, fistulas, and abscesses.
In contrast to extramammary Paget disease of other sites, perianal Paget disease (PPD) has a high frequency of associated regional internal cancers, most commonly rectal adenocarcinoma.
In contrast to extramammary Paget disease at other sites, Paget disease of perianal skin has been reported to have a high frequency of associated cancers.