The work will provide a reference to illustrate the synaptic, coherent propagating flows in the nervous extracellular space
of the brain.
Inhibition of MMPs activity by TIMPs prevents too extensive degradation of extracellular matrix and provides appropriate amounts of the matrix components and equilibrium of extracellular space
The second issue is to elucidate the down stream signaling that forces cells to release HMGB1 or other toxic molecules to extracellular space
and to clarify the down stream cellular dysfunctions of neurons and/or glia.
Further studies will be needed to assess the relative contributions of decreased import of extracellular CySS and decreased reduction of intracellular CySS in regulating the balance between CySS and Cys in the extracellular space
13) Transport of glutamate from extracellular space
is pH dependent and lowering pH slows or even reverses glutamate uptake.
It was also found that parameter R reflects the electrical behavior of the extracellular space
showing a decrease as the degree of lesion progresses from CIN 1 to CIN 2-3.
Most epithelial cells transport products of digestion and other essential substances such as water through the cell and into the extracellular space
beneath the tight junctions .
Given that non-selective adrenergic beta blockers have an effect on beta 2 receptors and affect Na and K homeostasis, there are two proposed mechanisms assumed to be responsible for the development of hyperkalemia such as renin-angiotensin-aldosterone system blockade and decrease potassium uptake from the extracellular space
into the cell.
Any patient with edema especially needs the intracellular electrolytes potassium and magnesium to keep water inside the cells rather than in the extracellular space
Microvesicles are larger than exosomes (100-1000 nm) and are released into the extracellular space
by outward budding of the cell membrane.
The A type particles after acquiring a membranous envelope were budded off into the extracellular space
as B type particles (Fig.
that the conductivity in the extracellular space
is proportional to the intracellular conductivity.
11) The paralytic symptoms and signs improve as the potassium returns from the intracellular space back into the extracellular space
The researchers theorize that neurons clogged with beta-amyloid become unable to function normally and eventually burst, dumping beta-amyloid into the extracellular space
where plaques then form.
By reversing the relative concentrations, it can also be used to introduce a substance into the extracellular space
, for example a precise dose of medicine in a tightly targeted tissue.