is a term used in muscle physiology that describes the process of converting an electrical stimulus (a nerve impulse) to a mechanical response (muscle-fiber contraction), Bett explains, and ion channels are proteins that act as pores in a cell membrane, permitting selective passage of potassium, sodium, and calcium molecules in and out of the cell.
Ca] is an inward current which is important in controlling the plateau phase of the AP and involved in the excitation-contraction coupling
in cardiac myocytes.
Several mechanisms, such as neuromuscular propagation, excitation-contraction coupling
, intracellular regulation, might be responsible for the decreases observed in evoked contractions and MVC (Bigland-Ritchie, 1984; Hill et al.
Energy expenditure occurs with excitation-contraction coupling
and calcium reuptake within the myocyte.
Abstract #2257: Effects of the Cardiac Myosin Activator CK-1316719 on Excitation-Contraction Coupling
in Ventricular Myocytes About Cytokinetics