10] He emphasized that Washington had been weakened not only by the bloodletting, but by other procedures as well (blistering, emetics
, and laxatives) and that his heart had been severely taxed.
Other mainstays of Halsey's practice included giving emetics
to induce vomiting, cathartics to trigger bowel movements and dispensing other popular medicines of the day, from snake root and caster oil to quinine, expectorants and various salts.
McVey added, "The commercial attraction and likelihood of improving the speed of action of a major analgesic product such as ibuprofen is self evident and we are therefore already applying the same CEFORM microsphere technology to additional products that would benefit from improvements in their speed of action, such as other analgesics, anti allergy compounds and anti emetics
First, its anti- emetic
research program has yielded the anti-emetics
Compazine(R) (prochlorperazine) and Kytril(R) (granisetron hydrochloride).
The introduction of highly emetic
chemotherapy agents (eg cisplatin) in the 1970s, and the failure of anti-dopaminergic drugs to control associated nausea and vomiting lead to the recognition that nausea and vomiting involved many more pathways and neurotransmitters than was previously understood.
potential of the chemotherapy and the prophylactic use of antiemetics each appeared to contribute to the overall severity of symptoms.
a 3-drug combination of 5HT3 serotonin receptor antagonist, dexamethasone and aprepitant on day 1 for chemotherapy agents with a high emetic
When rushed to the emergency department during the emetic
phase, CVS patients can present with blood in the vomitus due to prolapse gastropathy or Mallory-Weiss tears resulting from forceful heaves, erosive esophagitis, and aspiration.
Hypovolemia and pain also have "powerful" emetic
effects, he added.
After 10 mm, copper sulfate anhydride was administered orally in a dose of 50 mg/kg, then the number of retching (an emetic
action without vomiting gastric materials) was recorded during the next to mm.