Ehrlich tumor is a species-specific, transplantable neoplasia from malignant epithelium that corresponds to mice's mammary adenocarcinoma.
The main purpose of this study was to induce hypothyroidism in ovariectomized or non-ovariectomized adult female mice in order to create an experimental model that allowed the study of the effect of hypothyroidism on cell growth, viability, and characteristics of ascitic Ehrlich tumor from mammary adenocarcinoma.
Ascitic Ehrlich tumor cells were used in Swiss strain mice.
Ascitic liquid production in Ehrlich tumor has been credited mainly to hyperpermeability and vessels from peritoneal cavity microcirculation.
Although there are no classifications of Ehrlich tumor cells as dark and clear in the literature, this seem to be the most appropriate denomination considering the morphological characteristics observed.