There are major question remaining with regard to plant expression system and the oral edible vaccines
like how to move the vaccine through the anterior part of the gut (rumen and stomach) without degrading or inactivating the antigen itself.
For the next trials, the scientists plan to give participants one dose of the edible vaccine
, possibly in the form of yoghurt, which Marshall believes is ideal for people to eat as a vaccine.
Previous attempts at edible vaccines
included mashed potato that could prevent traveller's diarrhoea and GM rice to ward off allergies.
We hope edible vaccines
could be grown and used in those countries.
Case Study: Edible Vaccine
for Allergic Immunotherapy
Kalorama estimates that needle-free drug delivery methods--which include patches, edible vaccines
, pen injectors and more--will likely see a significant increase in revenues, with annual growth averaging 15.
Blood samples taken over the next 2 months revealed that 19 of 20 people getting the edible vaccine
had elevated concentrations of antibodies against Norwalk virus, although the rise varied between individuals.
Further the report analyses the steps to develop an edible vaccine
and the close miracles of science which transform the genetic materials in plants thereby leading them to being host candidates for edible vaccines
such as the role of transgenic plants.
Having an edible vaccine
further simplifies logistics.
During the event, a total of 10 sessions were conducted including 36 oral presentations on the top- ics covering different areas in biological research like molecular virology, forensic sciences, bioinformatics, proteomics, edible vaccines
, functional genomics, plant genomics, stem cells, systems biology, biopharmaceuticals and network biology.
, compounds to prevent HIV transmission, and insulin are just a few of the things scientists are working on cultivating in GE plants.
Medical molecular farming: expression of antibodies, biopharmaceuticals and edible vaccines
Research is underway, for example, to produce edible vaccines
within plants as a way of facilitating access to vaccines in countries where the distribution or refrigeration of medicines is poor.
, mucosally delivered vaccines, intranasal vaccines, vaccine patches and vaccine chips are all under development, with the latter expected to be commercialized within the next several years.
GMOs could offer edible vaccines
for asthma or allergies, and pest resistant breeding corn.