Enhanced vasculotoxic metal excretion in post-myocardial infarction patients receiving edetate
goiter: Euthyroid multinodular goiter; Co: cobalt; Cr: chromium; MOP: metal on polyethylene; MOM: metal-on-metal; EDTA: edetate
calcium disodium; DMPS: sodium 2,3-dimercaptopropane sulfonate; NAC: N-acetyl-cysteine; * the prosthesis has been implanted after the rupture of a previous ceramic hip implant.
It is also combined with edetate
calcium disodium for lead poisoning.
Deaths Resulting from Hypocalcemia after Administration of Edetate
The FDA alleged that Evers had violated the Federal Food, Drug, and Cosmetic Act (the Act) under misbranding provision by promoting and administering a chelating drug, calcium disodium edetate
(calcium EDTA), an FDA-approved drug for an indication not approved by the agency.
The sodium edetate
preferentially forms more stable complexes with polyvalent cations (e.
2% purified egg phosphatide with disodium edetate
or sodium metabisulphite added as a preservative (2).
Combined therapeutic potential of Meso 2, 3 dimercaptosuccinic acid and calcium disodium edetate
in experimental lead Intoxication in rats.
104) The doctrine of equivalents dispute centered on whether edetate
, a chemical required by the language of the claims, could reach via equivalence the accused product, which used calcium trisodium DTPA rather than edetate
Several drugs are used in the treatment of lead poisoning, including edetate
disodium calcium (CaEDTA), dimercaperol (British anti-Lewisite), D-penicillamine, and meso-2,3-dimercaptosuccinic acid (succimer).
Among the new entries are aluminum hydroxide adjuvant, disodium edetate
, ethyl lactate, hectorite, lactose spray dried, lauric acid, linoleic acid, raffinose, and saponite.
Dimercaprol is either used alone (arsenic, gold, and acute mercury) or combined with edetate
calcium disodium (lead).
Combined therapeutic potential of meso-2,3-dimercaptosuccinic acid and calcium disodium edetate
on the mobilization and distribution of lead in experimental lead intoxication in rats.
calcium disodium (CaNa2EDTA) promotes urinary excretion of lead and is used in children with levels greater than 45; it is administered IM or IV.
2] Another similar study used a formulation consisting of apomorphine, sodium metabisulphite, and sodium edetate