beta-lactamase

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  • noun

Synonyms for beta-lactamase

enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic

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References in periodicals archive ?
Further investigation on our study isolates could include the analysis of ESBL enzyme type, phylogenic group or sequence type, to determine any clonal relationship or association with multidrug resistance in our population.
Another study by Linscott et al evaluated the MicroScan ESBL plus ESBL confirmation panel.
Though CLSI described phenotypic confirmatory test is applicable for Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis, an attempt was made to look for ESBL production among other members of Enterobacteriaceae also.
One of the babies was last night named at an inquest as Hope Erin Evans, from Aberdare, who died on November 4 at Swansea's Singleton Hospital from the ESBL strain of E.
Disk diffusion test was performed for all Enterobacteriaceae isolates against ceftazidime (30 [micro]g), cefotaxime (30 [micro]g), ceftriaxone (30 [micro]g) and cefpodoxime (10 [micro]g) antibiotic disks (Hi-Media, Mumbai, India) to screen the isolates for potential ESBL production (5).
ESBL carriage was mapped onto minimum-spanning trees for the 2 isolate groups.
We also analyzed various risk factors to determine their association with infection by ESBL producing organisms.
The number of cases were reported from just seven of Scotland's 61 hospital labs and experts say the true figure of ESBL super E Coli is now in the thousands each year.
There have been 300 recorded cases of ESBL in the Telford area, and 28 of the first 105 people diagnosed are now dead.
Although drug resistant infections such as MRSA have been a key focus over recent years, our opinion leader research reveals new concerns with Gram negative organisms such as actineobacter, pseudomonas and ESBL producing strains.
DNA from 359 ESBL isolates (4) was screened for the presence of the EAEC transport regulator gene (aggR), located on the EAEC plasmid, by using a real-time PCR assay and the following primers and probe: AggR F 5'-CCATTTATCGCAATCAGATTAA-3' AggRR 5'-CAAGCATCTACTTTTGATATTCC-3 AggR_P Cy5-CAGCGATACATTAAGACGCCTAAAGGA-BHQ.
Tests have shown that a baby at the unit in Swansea's Singleton Hospital is carrying the antibiotic-resistant ESBL strain of the bug, but is not showing any signs of infection.
Background & objectives: Data on extended-spectrum [beta]-lactamases (ESBLs) produced by Gram-negative bacteria including KlebsieUapneumoniae especially molecular types of ESBL genes from India are limited.
pneumoniae, due to both ESBL production and porin deficiency (which elevated imipenem and meropenem minimum inhibitory concentrations (MICs) 4-7-fold, respectively) in a private hospital in Cape Town, was recently described.