Cumulative dose response
curve was constructed by plotting increasing concentrations of ranitidine on x-axis and the percent response on y-axis.
of weeds to methyl iodide and methyl bromide.
A model of molecular titration producing near-threshold dose response
is provided in Supplemental Material, "Molecular titration.
IN Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
, (1) the authors contend that the toxicological significance of alleged endocrine-disrupting chemicals ("EDCs") cannot be assessed using the traditional monotonic threshold dose-response curve.
This reward recognizes the research I have conducted in the past few years aiming to understand, using computer simulations, the nature of many experimentally observed nonlinear, including non-monotonic, biological dose response
curves in the low-dose region for a variety of chemicals," said Dr.
2) 98 (29- >1000) * opening Difficulty in inserting No dose response
LMA Swallowing 3.
Chapter 3: Uncertainty Modeling in Dose Response
Using Non-Parametric Bayes: Bench Test Results (Lidia Burzala and Thomas A.
Previously we reported that the rapid effect of BPA on the contractility of female cardiac myocytes is characterized by a nonmonotonic dose response
(Belcher et al.
The primary endpoint of the study was to determine whether there was a dose response
in the change in serum phosphorus from Baseline to Day 28 in the ITT group, using a regression analysis to evaluate this objective.
There is a huge demand for anticoagulant products that have a predictable dose response
and do not require monitoring in order to determine a patient's treatment dose.
The "model-averaged" dose response
predicted markedly lower risks than the LNT model for cerebrovascular disease (CVD) and for cardiovascular diseases excluding CVD.
The Phase II trial is designed as an open label, sequential, ascending dose study to evaluate the safety, tolerability and dose response
of NE-180 administered subcutaneously.
KEY WORDS: biologically based dose response
, dose--response model, low-dose risk, risk assessment, two-stage model.
Once-per-week dosing of ALTU-238 appeared to result in a consistent, linear dose response
of hGH and IGF-1 levels in the blood.
On the environmental side, Mushak--in both his letter and his commentary (Mushak 2009)--did not acknowledge that the largest-ever rodent cancer bioassay (24,000 mice) that was designed to determine the nature of the dose response
in the low-dose zone for carcinogens revealed hormetic responses for acetyl aminofluorene-induced bladder cancer and that this was affirmed by the 14-member Society of Toxicology expert panel convened to assess these findings (Society of Toxicology [ED.