Perjeta works in a different way to any other cancer medicine as it is the first in a new class of targeted treatments, known as HER2 dimerisation
inhibitors, which work to block cancer cell growth and survival signals.
PerjetaA is a first-in-class HER2 Dimerisation
Inhibitor (HDI) monoclonal antibody.
UV irradiation affects DNA by initiating thymine dimerisation
Also among the innovations were a new grade of polyester to make mineral water bottles, a new way of using ethylene dimerisation
to make butene-1 and a low-weight, low-cost front module for the new Smart car, created using Sabic Stamax plastic.
It is the first in a new class of targeted treatments, known as HER2 dimerisation
inhibitors (or HDIs), which work to block cancer cell growth and survival signals.
One way would be, for instance, to design molecules that specifically stop MITF dimerisation
Pertuzumab is a HER2-directed dimerisation
inhibitor which binds to HER2 at a different subdomain than trastuzumab.