The dexamethasone suppression test
, or DST, requires that the horse gives a small sample of blood, then be administered cortisone, and a follow-up blood sample be taken the next day.
By using the dexamethasone suppression test
and CRH stimulation test together, they are able to diagnose Cushing's syndrome with 98 percent accuracy, according to a recent NIH study.
Subsequently, urinary free cortisol (UFC) (normal range: <110[micro]g), urinary normetanephrine (normal range: 88-444 [micro]g/day) and urinary metanephrine (normal range: 52-341 [micro]g/day) were measured and the 1 mg overnight dexamethasone suppression test
(DST) was performed.
The literature supports that the overnight 1 mg dexamethasone suppression test
(DST), sensitivity and specificity 73% to 100% and 90%, respectively, appears to be the test of choice to rule out autonomous glucocorticoid production, Cushing's syndrome or subclinical Cushing's syndrome (sCS).
Methods: Records of patients with ECS from 1985 to 2006 were retrospectively reviewed that included the presenting manifestations, clinical symptoms and signs, biochemical investigations including plasma cortisol, ACTH and high dose dexamethasone suppression test
(HDDST), imaging modalities to localize the non pituitary source of ACTH production, management and follow up of these patients.
8 mcg/dL to a low-dose dexamethasone suppression test
07 [micro]mol/L after a repeated 1-mg dexamethasone suppression test
In the patient with an adrenal mass, a low-dose dexamethasone suppression test
is a good screening tool.