pinnatum responsible for the inhibitory effect on porcine detrusor muscle
The underlying mechanisms involve overactive detrusor muscle
or poor bladder compliance.
Characterization of the 5HT receptor potentiating neuromuscular cholinergic transmission in strips of human isolated detrusor muscle
Combined bladder dysfunction: results in the detrusor muscle
working in opposition to the external sphincter muscle.
Inhibition of the muscarinic receptors in the urinary bladder results in decreased urinary bladder contraction, increased residual urine volume, and decreased detrusor muscle
Surgically altered detrusor muscle
, such as augmentation cystoplasty 3.
the detrusor muscle
contracts); however, the external sphincter also contracts, creating detrusor-sphincter dyssynergia, or uncoordination.
Older antimuscarinic drugs lack selectivity for the M3 receptor, which regulates detrusor muscle
function, and often cause collateral blockade of central muscarinic M1 receptors, leading to cognitive impairment and sleepiness, explained Dr.
In elderly women with or without UI, the detrusor muscle
may become overactive without any neuronal loss.
This condition occurs when the detrusor muscle
contracts without warning, resulting in sudden and often noticeable leakage of urine.
Results from detrusor muscle
underactivity, bladder outlet obstruction, or both.
A flaccid anal sphincter may indicate poor detrusor muscle
A THE detrusor muscle
makes up the wall of the bladder.
Other health implications of urinary incontinence in people living with MS or spinal cord injury include skin irritation and ulcers, kidney failure4,11and recurrent urinary tract infections, which may lead to serious health consequences, if the overactivity of the detrusor muscle
is not treated.
16,17) The suprapubic position (2 cm superior to the symphysis pubis) relies on NIR light reaching the anterior wall of the bladder transcutaneously through the anterior abdominal wall to interrogate the detrusor muscle
in the anterior wall of the bladder.