She was concerned, however, that infants born to vaccinated mothers mounted only a blunted immune response to their primary DTaP vaccine
series, and wondered if responses would be blunted to other vaccines.
The other candidate Tdap vaccine, Adacel, is nearly identical to Sanofi Pasteur's currently licensed DTaP vaccine
, Daptacel, except that it contains lower levels of diphtheria toxoid and one of five pertussis antigens.
Since there is no established serologic correlate of protection for pertussis, the antibody responses to each of the three pertussis antigens (PT, FHA, and PRN) of the subjects in this study were compared with those seen in infants following receipt of GlaxoSmithKline's DTaP vaccine
The large potential market for DTaP vaccines
and other combination vaccines could provide substantial earnings and cash flow within the next two years.
The increase in the operating loss for the three months ended September 30, 1996, compared to last year, is primarily due to increased expenses for depreciation, materials, and labor, offset in part by a decrease in clinical trials and related expenses, as the Company adds personnel and seeks regulatory approval of its DTaP vaccine
in the U.
In addition, Abbott will market and distribute North American Vaccine's combination vaccines currently under development which will combine the DTaP vaccine
with antigens for the prevention of polio (IPV) and haemophilus influenza type b (Hib).
to contain sanofi pasteur's five acellular pertussis antigens, which are also used in its DTaP vaccine
for children (DAPTACEL(R)(a) vaccine, licensed in 2002) and its tetanus, diphtheria, and acellular pertussis (Tdap) vaccine for adults and adolescents (Adacel(R)(b) vaccine, licensed in 2005).
One of a new generation of vaccines that would make childhood immunization safer, Pertugen is the first DTaP vaccine
derived though the use of recombinant DNA technology to detoxify the pertussis toxin.
The approval of the fifth consecutive dose of DAPTACEL vaccine completes the FDA license for the entire five-dose DAPTACEL vaccine series enabling health-care professionals to administer the same brand of DTaP vaccine
for the series as recommended by the Centers for Disease Control and Prevention (CDC) Advisory Committee on Immunization Practices (ACIP), the American Academy of Pediatrics (AAP), and the American Academy of Family Physicians (AAFP).
The DTaP vaccine
will complement our existing pediatric nutritional and pharmaceutical product portfolio," said Thomas M.
To be fully protected against pertussis, every child needs to get five doses of the DTaP vaccine
by age seven.
Revenue in the quarter ended March 31, 1996 is from initial vaccine product sales following regulatory approval of its DTaP vaccine
8, 1996--North American Vaccine (AMEX:NVX) announced today that the Swedish Medical Products Agency has granted regulatory approval of the Company's acellular pertussis vaccine formulated as a combined DTaP vaccine
for the prevention of diphtheria, tetanus and pertussis (whooping cough).
Newly uncovered documents reveal that just weeks after the PHS/AAP recommendation, vaccine maker Smith Kline Beecham (now GlaxoSmithKline) wrote to the CDC suggesting a significant reduction of mercury exposure to children through use of the thimerosal-free DTaP vaccine
, Infanrix, which could meet the U.
The application seeks regulatory approval of the DTaP vaccine
for all primary and booster doses for infants and children in Sweden.