DNA polymerase

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  • noun

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the enzyme responsible for DNA replication

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References in periodicals archive ?
Fluorescence recovery assay: a continuous assay for processive DNA polymerases applied specifically to DNA polymerase III holoenzyme.
Like a standard DNA polymerase, it creates a nascent growing strand in the 5' to 3' direction, and it must start from a pre-existing, annealed, 3'-OH of a primer sequence.
Bacteria such as Escherichia coli are endowed with three specialised DNA polymerases.
8, 2012 /PRNewswire/ -- New England Biolabs (NEB) has released a novel DNA polymerase, Q5[sup.
60) The use of heat-stable DNA polymerases, developed from T.
coli cells begin to starve, the bacteria quadruple their expression of DNA Polymerase IV (Pol IV), a mutation-causing enzyme that is notoriously bad at copying DNA accurately.
Ganciclovir offers much improved efficacy against cytomegalovirus compared with the three other antiviral agents listed, but it also has an effect on host DNA polymerases.
Demand for DNA polymerases, restriction endonucleases and other workhorse laboratory enzymes will grow steadily; innovative products may also spur demand.
Central among them are DNA polymerases, the enzymes that choose appropriate nucleotides and stitch them together into new strands of DNA.
The DNA polymerases contained in Kapa Biosystems' reagents have been engineered through a process of molecular evolution and possess unique amino acid modifications that confer dramatic improvements to the function of the enzymes.
While enzymes of this class from different biological sources differ in terms of physical structure, capacity to catalyze side reactions, accuracy (fidelity) with which they work, and specific kinetic parameters, all DNA polymerases share the same core functional behavior in many key aspects.
We have found that CleanAmp(TM) dNTPs improve the performance of a number of thermostable DNA polymerases, allowing for simple conversion of any assay to a Hot Start version.
Other topics of the 28 articles include structural insights into translational fidelity, the function and formation of biological iron- sulfur clusters, eukaryotic translesion synthesis DNA polymerases, structural maintenance of chromosome (SMC) complexes, and antibiotics targeting ribosomes.