We then explored differentially methylated CpG sites in the placenta and in maternal blood cells as possible fetus-specific DNA markers
in maternal plasma.
Finding more fragments means researchers have a greater chance of finding DNA markers
for genes that control desirable traits.
These DNA sequences are useful resources for developing DNA markers
As of January 1997, more than 17,000 markers had been mapped in the mouse (one locus approximately every 200kb), including more than 5,000 genes and more than 10,000 (mostly microsatellite) DNA markers
John said: "Myra had the Yenesei DNA marker
, which can be traced to Siberia.
Hammer and Skorecki were part of the first research group 10 years ago that found the DNA marker
signature of the Cohanim, termed the Cohen Modal Haplotype.
The winning paper is: "Hypermethylated RASSFIA in Maternal Plasma: A Universal Fetal DNA Marker
that Improves the Reliability of Noninvasive Prenatal Diagnosis.
Typing 11-day-old larvae and using double-hybrid crosses to reduce homozygosity by descent and inbreeding depression in mapping families, Hubert & Hedgecock (2004) have produced the first low-density microsatellite DNA marker
maps for the Pacific oyster.
At the Ames lab, DNA marker
technology is being used to glean valuable genetic intelligence on the rootworms.
It must be stressed, however, that the possibility of clinical implementation of fetal DNA as a screening tool will have to await the discovery of a reliable gender-independent fetal DNA marker
that can be assayed by real-time PCR.
However, the difference between a DNA marker
of disease and susceptibility is not always clear.
A molecular test is available for chinook salmon that is based on a DNA marker
specific for the Y chromosome (8).
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