All DNA constructs
were linearized by Fsp I before transfection.
Based on the current average market cost of similar DNA constructs
, the total market value of these prizes exceeds $500,000.
While our engineers work to develop advanced devices capable of accessing difficult-to-reach tumors, the Discovery Research team is investigating new DNA constructs
and targets focused on defeating cancer's ability to evade the immune system, allowing the patient's immune system to recognize and attack the tumor(s).
We and others have previously shown that DNA constructs
expressing conserved influenza proteins induce antibody and T-cell responses and protect against H3N2 heterosubtypic challenge (25-27).
Gen9 is a privately held company with a portfolio of next-generation gene synthesis technologies that enable the high-throughput, automated production of DNA constructs
at lower cost and higher accuracy than previous methods.
The Gen9 technology allows for the lowest-cost and highest-quality DNA constructs
Protein Potential's Products and Services group provides high quality recombinant proteins and DNA constructs
to corporate, government, and academic clients.
These patents relate to metabolic engineering and the production of renewable chemicals enabling the construction of genome-sized DNA constructs
as well as the production of valuable petrochemicals from biological sources.
encoding a chimeric T-cell receptor and a method of making a redirected T cell expressing a chimeric T cell receptor by electroporation using naked DNA encoding the receptor are also disclosed.
The inaugural G-Prize contest, conceived and exclusively sponsored by Gen9, was launched to foster creative and innovative approaches for using synthetic DNA constructs
to advance industries including chemical and enzyme production, biofuels, pharmaceuticals, and even data storage.
In vivo transfection kits supplemented by over 100 pre-optimized in vitro transfection reagents for cancer cell lines, electroporation buffers, and transfection controls (GFP plasmids, inducible expression DNA constructs
, siRNA molecules that induce apoptosis, cell cycle arrest, or serve as a non-silencing RNA control in gene silencing experiments).
The compositions are DNA constructs
that comprise novel arrangements of T-DNA molecules containing genes of interest, positive selectable marker genes, and conditional lethal genes.
Gen9 has developed a unique technology to synthesize DNA constructs
and has used it to build a novel fabrication capability for next-generation gene synthesis known as the BioFab([R]) tool.
Idera's gene-silencing oligonucleotides (GSOs) are single-stranded RNA or DNA constructs
with two exposed 3'-ends that are complementary to targeted mRNA sequences of therapeutic interest.
Using Inovio's synthetic consensus design approach the company has created universal DNA constructs
for key virus clades (branches) within the Type A subtypes H1N1, H2N2, H3N2, and H5N1 as well as Type B.