cytotoxic T cell

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  • noun

Synonyms for cytotoxic T cell

T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it

References in periodicals archive ?
It increases the number of tumour-infiltrating cytotoxic T-cells and dendritic cells.
Subcutaneous panniculitis-like T-cell lymphoma is a rare cytotoxic T-cell lymphoma that can be misdiagnosed as a benign panniculitis due to histologic similarities between the 2 entities.
The research demonstrated that the Geron compounds increased the proliferative capacity of cytotoxic T-cells and their ability to produce a virus-fighting molecule, gamma Interferon.
Antibodies bind to and neutralize infectious viral particles while cytotoxic T-cells attack host cells, which synthesize the virus, before the virus is released into the circulation.
The chicken's immune system produces cytotoxic T-cells whose function it is to target and destroy infected cells," explains Lillehoj.
Moreover, this was the first time an adjuvant has shown the ability to induce CD8+ cytotoxic T-cells in humans.
The mechanism is unclear, but extrapolating from familial form, deranged cytokine interaction between histiocytes, cytotoxic T-cells and natural killer (NK) cells due to defective perforin[sup.
He noted that immune responses based on production of specific cells, known as cytotoxic T-cells, have been largely neglected in evaluating the efficacy of flu vaccinations.
Cytotoxic T-cells, also referred to as CD8 T-cells, are required to target and eliminate pathogen-infected or cancerous cells.
Studies have shown that T-cell vaccination resulted in the in vivo induction of CD8+ cytotoxic T-cells and CD4+CD25+FoxP3 Tregs specific for T-cell vaccine.
There is compelling research showing that pre-existing CD8-positive T-cells, also known as cytotoxic T-cells, are associated with favorable clinical response to anti-PD-1 therapy in melanoma.
Studies of T-cell vaccine have indicated that T-cell vaccination with peripheral blood-derived autologous myelin-peptide selected T-cells in MS patients resulted in the in vivo induction of CD8+ cytotoxic T-cells and CD4+CD25+FoxP3 Tregs specific for T-cell vaccine.
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