Acute rejection developed only in those with detectable levels of donor-specific cytotoxic T lymphocyte
precursors before conversion.
The enhancement of T helper activation probably augments cytotoxic T lymphocyte
activity by stimulating dendritic cells.
Vaccinia virus-specific CD8+ cytotoxic T lymphocytes
CytoDyn's CRO, will present Phase I/II data demonstrating the antiviral effects and absence of liver toxicity in individuals who have failed Highly Active Antiretroviral Therapy (HAART) after Cytolin(R) was used to protect CD4+ T lymphocytes from the anti-self, anti-CD4 cytotoxic T lymphocytes
that proliferate uniquely in humans infected with HIV.
HLA proteins attach to antigens (such as virus particles) within an infected cell and then display the antigens at the cell surface to induce the destruction of the infected cell by cytotoxic T lymphocytes
Rotavirus-specific cytotoxic T lymphocytes
appear at the intestinal mucosal surface after rotavirus infection.
The authors demonstrated that the anti-tumor effect of talabostat appears to involve tumor-specific cytotoxic T lymphocytes
(CTL) and protective immunological memory.
When combined with disease-specific antigens, the technology creates JuvaVax(TM) vaccines capable of activating substantial antibody- and cell-mediated immune responses, particularly induction of cytotoxic T lymphocytes
The researchers believe that cytotoxic T lymphocytes
play a role in the pathogenesis of emphysema.
Next, they isolated the cytotoxic T lymphocytes
, killer white cells that destroy tumors.
The authors had previously found that telomere loss in cytotoxic T lymphocytes
(CTLs), the cells responsible for killing HIV-infected cells, was accelerated in AIDS patients, and contributed to the loss of anti-HIV activity that occurs during disease progression.