deamination

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  • noun

Synonyms for deamination

removal of the amino radical from an amino acid or other amino compound

References in periodicals archive ?
Modulation of activation-induced cytidine deaminase by curcumin in Helicobacter pylori-infected gastric epithelial cells.
Chemoresistance to Ara-C can arise from a number of factors influencing the rate of Ara-CTP formation and incorporation into DNA (5), including low drug uptake, conversion into Ara-uracil by cytidine deaminase, or dephosphorylation of active metabolite by cytoplasmic nucleotidase (6).
The dinucleotide, S110, is highly resistant to cytidine deaminase degradation in pre-clinical studies.
The study of Robbiani et al [7] demonstrated an association between DNA damage response pathways and the development of B-cell lymphoma in cells over-expressing activation-induced cytidine deaminase (AID).
The dinucleotide S110 is highly resistant to cytidine deaminase degradation in pre-clinical studies.
In brief, a RNA-specific cytidine deaminase, apoB mRNA editing enzyme catalytic complex 1 (apobec-1), binds to and acts on the cytosine molecule at base 6666 of the mRNA to create a uracil, which leads to the glutamine 2153 (CAA) codon being converted to a termination (UAA) codon (2).
SHM is a controlled process of introducing variability into the binding region of an antibody gene sequence and is catalyzed by the B-cell specific enzyme, Activation-Induced Cytidine Deaminase (AID).