calanthe

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Words related to calanthe

any of various showy orchids of the genus Calanthe having white or yellow or rose-colored flowers and broad leaves folded lengthwise

References in periodicals archive ?
We are delighted that Cytheris has selected us again as their CMO, to manufacture IL-7 in support of their expanded clinical trial program.
As we move towards large scale production of our IL-7 biotherapeutic, we are pleased to continue our strong working relationship with Laureate Pharma," said Michel Morre, DVM, President and CEO of Cytheris.
With these initial results in mind, the real breakthrough for IL-7 therapy lies in the administration of CYT107 shortly after the massive antigen drop triggered by treatment with two HCV DAAs, a drop which usually occurs less than two weeks following the start of antiviral treatment" commented Therese Croughs, MD, Chief Medical Officer of Cytheris.
Currently, Cytheris is conducting multiple international investigations of IL-7 in HIV, HCV, HBV, post-BMT and cancer.
The Cytheris board, composed of the Bioam Investment Fund represented by Chantal Parpex, and two of the co-founders, Etienne Bouillot and Michel Morre (company chairman and CEO), welcomes two new members who will provide additional expertise through this scale up period:
Based in Vanves, France and in Rockville, Maryland USA, Cytheris (CYtokine THERapy for the Immune System) is a French Biotechnology company focused on the development of new therapies for the immune system.
The selection of CYT107 for study in immunotherapy trials conducted by the outstanding investigators from CITN member sites is a clear recognition of the potential of this cytokine to play an important role in the development of new approaches to the treatment of various cancers," said Michel Morre, DVM, President and CEO of Cytheris.
Conducted as a collaborative effort of the Centre Leon Berard (the study sponsor), ImmunID Technologies, and Cytheris, the study, known as ELYPSE-7, is designed to evaluate whether CYT107 treatment is able to correct lymphopenia post-chemotherapy in advanced cancer patients and whether the correction of this lymphopenia by restoration of the immune system will result in a broadening of the repertoire of T cells and a reduction in the risk of severe haematological toxicity, tumor progression and early death.
2011 May; 11(5):330-42) entitled "Harnessing the Biology of IL-7 for Therapeutic Application", the authors conclude that despite the impressive biological effects of IL-7 on T cell populations, the essential issue regarding clinical development of this cytokine is the need to show that the biological effects of IL-7 translate to improved clinical outcomes such as prolonged survival or cure," said Michel Morre, DVM, President and CEO of Cytheris.
CD4 T-cell depletion in gut mucosa is an early and key pathogenic event in HIV infection that is associated with T-cell activation1,2," said Michel Morre, DVM, President and CEO of Cytheris.
Preclinical studies like the one reported here, that combine a well defined animal model with definitive clinical end points together with a precise elucidation of the immune mechanisms supporting the therapeutic effect, have great prospective value," said Michel Morre, DVM, President and CEO of Cytheris.
PARIS -- Cytheris SA, a clinical stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced interim results from a Phase I clinical trial of its investigational drug candidate, recombinant human Interleukin-7 (CYT107), in the treatment of post-transplant patients with T-cell depleted (TCD) bone marrow or peripheral blood stem cell transplants.
PARIS -- Cytheris SA, a clinical-stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced the publication of a case study report based on successful treatment of Progressive Multifocal Leukoencephalopathy (PML) with combination therapy consisting of two investigational agents, Cytheris' recombinant human interleukin-7 (CYT107) and CMX001, an investigational, oral broad-spectrum antiviral drug (Chimerix, Research Triangle Park, NC) in the Journal of Antimicrobial Chemotherapy.
PARIS -- Cytheris SA, a clinical stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced the initiation of Phase II clinical trial of the company's investigative immunomodulatory agent, CYT107 (rhIL-7), in combination with two potent antiretroviral drugs represented by the integrase inhibitor raltegravir (ISENTRESS([R]) - Merck & Co.
PARIS -- Cytheris SA, a clinical stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced that it has begun enrolling patients in INSPIRE 3, a Phase II clinical program evaluating the effect of repeated cycles of the company's investigative immune-modulator, recombinant human Interleukin-7 (CYT107), in the treatment of chronically HIV-1 infected patients classified as Immunological Non-Responders (INR) after at least 24 months of highly active anti-retroviral therapy (HAART).