The excess Cortisol found in Cushing syndrome
can result from certain steroid medications or from tumors of the pituitary or adrenal glands.
Researchers at NIHs Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), in collaboration with researchers at other institutions in the United States, France and Canada, scanned tumor and cell tissue from 146 children with pituitary tumors evaluated for Cushing syndrome
at the NIH Clinical Center.
Iatrogenic Cushing syndrome
due to topically used steroid; case report.
Messina MF, Valenzise M, Aversa S, Arrigo T, De Luca F Iatrogenic Cushing syndrome
caused by ocular glucocorticoids in a child.
However, before a diagnosis of PCOS is made, both CAH and Cushing syndrome
should be ruled out since they will manifest similarly (3).
due to ectopic adrenocorticotropin secretion by oncocytic thyroid nodule.
due to an adrenal tumor is treated with surgery to remove the tumor and often the entire adrenal gland.
Prolonged exposure to high cortisol levels causes Cushing syndrome
, which is characterized by weight gain, particularly in the trunk and face.
Anthropometric and metabolic characteristics and non-alcoholic fatty liver disease data of subjects with non-functioning adrenal adenomas, Cushing Syndrome
and control subjects Adrenal Cushing Control P * p adenoma Syndrome Subjects dagger double ( n = ( n = 20 ( n = dagger 130 ) ) 170 ) Age 56.
Adrenal cortical hyperplasia is often seen in patients with Cushing syndrome
(the result of hyperproduction of cortisol) and less commonly in Conn's disease.
Ritonavir-fluticasone interaction causing Cushing syndrome
in HIV-infected children and adolescents.
While adrenal carcinoma accounts for only approximately 5-10% of cases of Cushing syndrome
; approximately 40% of patients with both Cushing syndrome
and an adrenal mass have a malignant tumour (2, 3).
Children experience cognitive decline despite reversal of brain atrophy one year after resolution of Cushing syndrome
As James Findling (11) once said, "if you have never missed the diagnosis of ACTH-dependent Cushing syndrome
, and you have never been fooled attempting to establish its cause, you should refer your patients with suspected hypercortisolism to somebody who has" (personal communication).
In this collection of ten articles international experts describe their research in adrenal development and disorders, steroidogenic enzymes, adrenal androgens in humans an nonhuman primates, androgen synthesis and its clinical implications, a new form of congenital adrenal hyperplasia, long-term outcomes of prenatal treatment of congenital adrenal hyperplasia, syndromes involving adrenocorticotropin resistance, corticotrophin-independent Cushing Syndrome
, and adrenal steroidogenesis and arterial hypertension.