In 20 consecutive blood samples from patients with known chronic lymphocytic leukemia, a total leukocyte count and a differential were done in a Coulter Counter
STKS, and glycohemoglobin was measured simultaneously in the Abbott IMx (ion capture technology, fluorescence quenching), the Bayer DCA 2000 (immunologic latex agglutination), and the Bio-Rad DiaSTAT (low pressure liquid chromatography).
Shortly thereafter, the Coulter Principle was adopted in the first automated hematology analyzer, the Coulter Counter Model A.
Koepke, MD, professor emeritus at Duke University in Durham, NC, and one of the first to purchase the Coulter Counter Model A when he worked for the University of Kentucky Medical Center in Lexington, KY.
In order to fully appreciate the Coulter Counter, one needs to view its significance in relation to the medical technology of its day--in this case, the hundred-year-old method of visually counting cells with a counting chamber and microscope," says Alan Jones, MD, who became friends with Wallace Coulter when Wallace personally installed an early Coulter Counter model in Jones' laboratory at Children's Medical Center in Boston in 1958.
While the previous technology provided a standard precision deviation of plus or minus 10%, the Coulter Counter reduced this deviation to plus or minus 1%," says Jones.
With wireless technology linked to automatic monitoring kit to monitor things like TDS (total dissolved solids, which if high is a strong indicator of lack of due care and attention by the cooling tower owner/operator), coulter counters
, active bacteria destruction kit such as, but not limited to, UV or UV coupled to sonicators or a pressure cylinder (akin to the Hugh's Press) for disrupting possible host eukaryotes (e.