Another finding is that pups with mostly white coat color and/or blue eyes have congenital deafness
Genetics of congenital deafness
in the Palestinian population: multiple connexin 26 alleles with shared origins in the Middle East.
1, 2) Congenital deafness
caused before birth may be the result of genetic defects, prenatal infections in the mother such as rubella, influenza and congenital syphilis, incompatible mother/child blood type and certain drugs such as thalidomide, streptomycin and neomycin.
Sharon Duchesneau and Candy McCullough, who have both been deaf since birth, were turned down by a series of sperm banks they approached looking for a donor suffering from congenital deafness
Insurance would not cover the enormous expense of the hearing aids: Sophia's congenital deafness
was a "pre-existing condition.
Both children were born with impaired hearing after the couple, in their thirties, sought out a deaf man to be the sperm donor A Washington sperm bank had refused to provide a deaf donor, saying congenital deafness
is precisely the sort of condition that gets a would-be donor eliminated.
Hearing can be damaged at birth - known as congenital deafness
- but untreated infections can lead to permanent damage.
The Jervell-Lange-Nielsen Syndrome is more severe, is the rarer homozygous form, and is associated with congenital deafness
The likely explanation is as follows: although heterozygous KVLQT1 mutations act by a dominant-negative mechanism, some functional KVLQT1 potassium channels till exist in the stria vascularis of the inner ear Therefore, congenital deafness
is averted in patients with heterozygous KVLQT1 mutations.
However, from the points made above, we argue that this masks a deeper conflict between descriptions of deafness (here we mean congenital deafness
, not that acquired later in life) as a handicapping condition to be `cured' or `fixed' by technological advances such as the cochlear implant, versus those descriptions of deafness as a viable and enjoyable socially-constructed life (Marschark 1993).
Type I disease is characterized by profound congenital deafness
with lack of vestibular function and childhood onset of RD.
Genetic flaws account for about half the incidence of congenital deafness
, but researchers estimate that mutations in more than a hundred genes may trigger such hearing loss.