Novel and unexpected insights into receptor topology, conformation
and compound binding have been revealed, showing major differences compared to the many already known Family A structures, such as beta-adrenergic receptor.
ab initio LCAO/LDA calculations which contains two-electron integrals has been undertaken to also calculate the electronic structure for the four different conformations
21) In oligoesters containing 1,4-CHDA, the equilibrium is relevant to conformations
commonly used in industrial applications as an average of the rates corresponding to cis and trans configurations formed during the polymerization reaction.
61 A when those side-chains that adopted drastically different conformations
are excluded from comparison.
Since circular dichroic (CD) spectra are very sensitive to conformational differences, they are useful in studying solution conformations
of NaAD Bound to NAD-Synthetase Determined by Transferred Nuclear Overhauser Effect Spectroscopy.
These extended chain conformations
reduce the free volume available for rotational motion.
Integral Molecular's Lipoparticle technology represents a stable, cell-free solution for displaying high concentrations of membrane proteins in their native conformations
for antibody and drug discovery applications.
Investigations will be carried out to ascertain the impact of the presence of an electric field and the capacity to tune the strength in order to enable improved understanding and selection of protein conformations
on tissue scaffolds, towards enhancing cell surface interactions, healing of misfolding and facilitating the restoration of the structure and function of diseased tissues.
From this vantage point, students can distinguish the two ethane conformations
Two main different chain conformations
in the crystalline state of sPP are known, a twofold helical [(ttgg).
Because of this micro-Brownian movement, rubber chains can assume an extremely large number of conformations
In silico method relies on prediction of hidden conformations
of target proteins
In order to increase inhibitor selectivity toward a desired target kinase, the focus has turned to developing inhibitors which bind to inactive conformations
or allosteric sites.
In addition to the `on' and `off' conformations
proposed in classical models of estrogen receptor action, it is now apparent that intermediate conformations
are possible, each of which seems to be associated with a different spectrum .