Called a "coenzyme" because of its unique ability to participate in chemical reactions but remain at steady-state levels in the cell, coenzyme Q10 plays a central role in energy metabolism.
Human neuronal coenzyme Q10 deficiency results in global loss of mitochondrial respiratory chain activity, increased mitochondrial oxidative stress and reversal of ATP synthase activity: implications for pathogenesis and treatment.
Specificity of coenzyme Q10 for a balanced function of respiratory chain and endogenous ubiquinone biosynthesis in human cells.
Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient.
Restoration of the behavioral rates and lifespan in clk-1 mutant nematodes in response to exogenous coenzyme Q(10).
Coenzyme Q supplementation protects from age-related DNA double-strand breaks and increases lifespan in rats fed on a PUFA-rich diet.
The reduced form of coenzyme Q10 decreases the expression of lipopolysaccharide-sensitive genes in human THP-1 cells.
Modifications of plasma proteome in long-lived rats fed on a coenzyme Q10-supplemented diet.
Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy.
Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction.
Treatment of statin adverse effects with supplemental Coenzyme Q10 and statin drug discontinuation.
Role of concomitant coenzyme Q10 with statins for patients with hyperlipidemia.
Coenzyme Q10 in cardiovascular disease with emphasis on heart failure and myocardial ischaemia.
Is coenzyme Q10 helpful for patients with idiopathic cardiomyopathy?
The effect of coenzyme Q10 in patients with congestive heart failure.