Co-agonist synonyms, Co-agonist antonyms - FreeThesaurus.com
agonist (redirected from Co-agonist)
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Synonyms for agonist
the principal character in a work of fiction
someone involved in a contest or battle (as in an agon)
a muscle that contracts while another relaxes
(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction
References in periodicals archive
Second, it seems at least theoretically possible to include circulating factors other than gut hormones in an analogous single-molecule co-agonist
," he added.
Lilly already has several multi-specific therapeutics in preclinical development, including a co-agonist
peptide being studied as a potential treatment for diabetes that is anticipated to enter clinical development by the end of this year.
5, 2010 /PRNewswire/ -- EnVivo Pharmaceuticals today announced it has discovered that EVP-6124, its alpha-7 nicotinic acetylcholine receptor agonist, possesses a novel mechanism not previously seen in the scientific community: it acts as a co-agonist
with Acetylcholine (ACh) to enhance cognition.
Licostinel, an NMDA receptor antagonist acting at the glycine co-agonist
site, was studied in a series of Phase I clinical trials from 1995 until earlier this year.
This research increases our understanding of how EVP-6124 enhances synaptic transmission in the brain and acts as a co-agonist
in combination with the body's own natural acetylcholine response to enhance cognition," said Gerhard Koenig, Ph.