agonist

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  • noun

Synonyms for agonist

the principal character in a work of fiction

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someone involved in a contest or battle (as in an agon)

a muscle that contracts while another relaxes

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(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction

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References in periodicals archive ?
Second, it seems at least theoretically possible to include circulating factors other than gut hormones in an analogous single-molecule co-agonist," he added.
Lilly already has several multi-specific therapeutics in preclinical development, including a co-agonist peptide being studied as a potential treatment for diabetes that is anticipated to enter clinical development by the end of this year.
5, 2010 /PRNewswire/ -- EnVivo Pharmaceuticals today announced it has discovered that EVP-6124, its alpha-7 nicotinic acetylcholine receptor agonist, possesses a novel mechanism not previously seen in the scientific community: it acts as a co-agonist with Acetylcholine (ACh) to enhance cognition.
Licostinel, an NMDA receptor antagonist acting at the glycine co-agonist site, was studied in a series of Phase I clinical trials from 1995 until earlier this year.
This research increases our understanding of how EVP-6124 enhances synaptic transmission in the brain and acts as a co-agonist in combination with the body's own natural acetylcholine response to enhance cognition," said Gerhard Koenig, Ph.