1) Clostridium sordellii
is a common soil and enteric bacterium that has presented in a very small number of obstetric and gynecologic cases, including following childbirth (vaginal delivery and caesarian section), medical abortion, and in other gynecologic and non- gynecologic conditions.
While deadly infections are rare, the Clostridium sordellii
bacterium is actually quite common.
In its "Public Health Advisory," the FDA indicates that it is working with the manufacturers of RU486 and misoprostol tablets to make sure that neither product was contaminated with the Clostridium sordellii
In the past 17 years CryoLife has processed some 250,000+ pieces of human tissue from more than 60,000+ donors, without a single known incidence of Clostridium sordellii
Antibiotic-induced colitis: implication of a toxin neutralised by Clostridium sordellii
Leukemoid reactions have been reported in postpartum women with Clostridium sordellii
sepsis and are characterized by striking degrees of leukocytosis (66-200 X [10.
When Brian Lykins died after receiving a bone graft infected with the bacterium Clostridium sordellii
, his family filed suit against CryoLife, the Kennesaw, GA company that supplied the bone.
Clostridial disease caused by Clostridium sordellii
seems to be cropping up more and more at laboratories,'' said independent veterinary adviser Chris Lewis.
However, providers of donated tissue have been under increased scrutiny by regulatory authorities, the medical community, and the public following the reported death in November 2001 of a recipient of an allograft (tissue transplant) from a non-TBI tissue contaminated with Clostridium sordellii
(an anaerobic spore and toxin-forming organism) and of 54 similar non-TBI related cases investigated by the Centers for Disease Control and Prevention (CDC).
The three authors examined 45 cases of Clostridium sordellii
infection occurring between 1927 and 2006.
This regimen, not approved by the Food and Drug Administration but widely used, was associated with all five fatal Clostridium sordellii
infections reported after medical abortion in the United States and Canada.
Most of the known maternal fatalities are from a type of toxic shock syndrome caused by Clostridium sordellii
All the women developed uterine infections with Clostridium sordellii
, a microbe that rarely attacks people but that can cause toxic shock when it does.