(redirected from Chymase)
Also found in: Dictionary, Medical, Encyclopedia, Wikipedia.
  • noun

Synonyms for chymosin

an enzyme that occurs in gastric juice

References in periodicals archive ?
Tryptase and chymase enzyme activity in the MCG preparation was measured as described previously (17).
Skin mast cell promotion of matrix remodeling in burn wound healing in mice: Relevance of chymase.
Distribution, activation and tryptase/ chymase phenotype of mast cells in the rheumatoid lesion.
Preformed mediators stored in cytoplasmic granules include histamine, tryptase, proteoglycans, chymase, carboxypeptidase A, and heparin.
Release of the mucosal mast cell granule chymase, rat mast cell protease II, during anaphylaxis is associated with the rapid development of paracellular permeability to macromolecules in rat jejunum.
The cascade of enzymes that break down collagen is also being investigated; among them is chymase, an enzyme that activates collagenase, which destroys collagen.
Key classes of mechanism of action include Anti-inflammatory molecules, Immunomodulators which included immunosuppresants, NF-kB Inhibitors and blockers, Calcenurin Inhibitors, Inteleukin inhibitors, keratinocyte inhibitors, anti-neoplastics, vaccines, histmaine H1-antagonists, TSLP interaction inhibitors, phosphodiesterase 4 (PDE4) inhibitor, chymase inhibitors, selective glucocorticoid receptor agonist, selective cannabinoid 2 receptor agonist, RAFT Modulator, cytokine modulator and alpha-1 proteinase inhibitors.
Many preformed mediators are involved in an anaphylactic reaction, including histamine, tryptase, chymase, mast cell carboxypeptidases, platelet activating factor and others.
The mediators released include tryptase, chymase, histamine, platelet-activating factor, cytokines, and others, as well as prostaglandin and leukotriene synthesis.
An advantage of the CT-proET-1 assay described here is that the CT-proET-1 fragment might be not subject to rapid turnover (16), whereas bigET-1 is an intermediary product in the biogenesis of ET-1 and is further cleaved by the action of ECE-1 and chymase into the active vasoconstrictor peptides ET-1 and ET-1(1-31), respectively.