Preimplantation genetic diagnosis (PGD) has been used for the identification of chromosome abnormalities
in couples who are at risk for either aneuploidy, based on maternal age, or an unbalanced parental karyotype chromosome rearrangement (such as translocations and inversions).
were designated and described according to the ISCN (An International System for Human Cytogenetic Nomenclature) 2005 .
Yet Wells and Delhanty report that some embryos that look healthy when viewed through a microscope have severe chromosome abnormalities
and would have little chance of producing a viable pregnancy.
The verifi([R]) prenatal test is a blood test that analyzes genetic material (or DNA) naturally found in a pregnant woman's blood to detect the most common fetal chromosome abnormalities
Unlike Turner syndrome, these structural X chromosome abnormalities
may be inherited, and thus have implications for the woman's parents, siblings, and/or children.
Embryo morphology developmental rates and maternal age are correlated with chromosome abnormalities
Franssen of the Center for Reproductive Medicine, Academic Medical Center, Amsterdam, and her associates analyzed 705 couples who had experienced recurrent miscarriage and had been tested for chromosome abnormalities
Cytogenetic analysis of soft tissue sarcomas: recurrent chromosome abnormalities
in malignant peripheral nerve sheath tumors (MPNST).
By screening the implanted eggs, doctors hope to avoid miscarriages or chromosome abnormalities
which are more common in older mothers.
Adolescents with sex chromosome abnormalities
(SCA), who have been studied since infancy by the researchers, were evaluated for "adolescent psychosocial impairment" as defined by the American Psychiatric Association.
Data from Additional Patients Confirms High Accuracy in Detection of Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
Rowley's discoveries of consistent chromosome abnormalities
in leukemia secured a common agreement by the 1970s among scientists, physicians, and the general public that cancer is, in fact, a genetic disease.
7 chromosome abnormalities
per 1,000 white blood cells in newborns from mothers with low exposure to PAHs and 7.
A thymoma with clonal complex chromosome abnormalities
As a group, sex chromosome abnormalities
are more prevalent at the time of birth than autosomal trisomies, such as Down syndrome, and detecting these anomalies continues to remain an unmet medical need despite advances in fetal cell-free DNA testing.