David Julius of the University of California, San Francisco and his colleagues wondered whether pain-inducing venom ingredients might activate the dual-purpose cell-surface
To get inside the lining cells on their way to the rest of the body, CVBs need to attach to a cell-surface
receptor that's buried within the tight junction.
This protein is the primary cell-surface
receptor that is commandeered by HIV, which uses it to enter white blood cells.
Teasing apart the complex circuitry of the brain might someday proceed with the flip of a switch, now that scientists have invented a light-responsive version of a common class of cell-surface
protein found in the nervous system plays a central role in a chronic-pain condition known as neuropathy, a new study in rodents suggests.
DCC codes for a cell-surface
receptor that binds to netrin-1, which scientists had previously linked to nervous system development.
These scientists' initial suspicion centered on neurotransmitter receptors, the cell-surface
proteins that respond to the chemical signals that nerve cells secrete.