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In summary, in a period of 2-3 weeks we identified ~162 proteins from peptides and protein fragments bound to carrier proteins from ovarian cancer patient serum samples.
s Reagent Proteins division announced today that it has submitted a Biologics Master File (BMF) to the United States Food and Drug Administration for its cGMP grade CRM197 carrier protein to support the development of conjugate vaccine products by its partners.
But it was the last group, the ones that got the corrole with the carrier protein, that experienced the most therapeutic effect," Medina-Kauwe added.
6) This is a significant number on its own, but the situation may be even worse when accounting for the fact that the majority of the hormone is bound to carrier proteins including sex hormone binding globulin (SHBG) and albumin and, as such, may not be available for tissues to use.
Washington, Dec 05 ( ANI ): A research team has found a way to stabilize hemoglobin, the oxygen carrier protein in the blood, a discovery that could lead to the development of stable vaccines and affordable artificial blood substitutes.
Battesti and Bouveret (6) have shown that during fatty acid starvation (p)ppGpp synthetase activity of SpoT is regulated through an interaction of the TGS domain of the enzyme with the acyl carrier protein (ACP), a central co-factor in fatty acid biosynthesis.
259) hypothesized that associations might be modified by a common variant allele of the aminolevulinic acid dehydratase (ALAD) gene, which encodes the primary carrier protein for lead in blood.
The reference gene are stearoyl carrier protein desaturase 2 (SAD)", said a Danish Plant Directorate spokesman.
Triclosan is known to act on enoyl-acyl carrier protein reductase, called Fab 1.
Preliminary experiments have provided evidence for an unusual mechanism of modular polyketide synthase chain release in enacyloxin biosynthesis, involving intermolecular condensation of an acyl carrier protein (ACP)-bound thioester with the C-3 hydroxyl group of (1R, 3R, 4S)-3,4-dihydroxycyclohexane carboxylic acid (DHCCA).
The Pfenex CRM197 currently being manufactured at Serum Institute is also being used by Serum Institute as the carrier protein for its own internal pneumococcal polysaccharide conjugate vaccine programs.
For the development of the calpastatin immunosensor, an antibody--Mouse anti Calpastatin, was conjugated to an acceptor fluorophore, Alexa Fluor 546, while the carrier protein, Protein G, was conjugated to the donor fluorophore, Alexa Fluor 594.
The solution called for a 'conjugate' vaccine, one that's attached to a carrier protein equipped with a specific immunogenic property.
The seventeen chapters have titles: Niche marketing for new oilseeds - an industrial perspective; Influences of findings in nutrition on the fats on oils industry; Environmentally acceptable lubricants; Resource allocation in developing oilseeds; Phosphoenolpyruvate metabolism of developing oilseeds; Regulation of lipid synthesis in castor seeds - analysis of the in vivo acyl-acyl carrier protein pools; Lipid biosynthesis in pea root plastids and some effects of glycolitic intermediates; Lipid biosynthesis in micropore-derived embryos of Brassica napus L; Fatty acid elongation in seeds of arabidopsis thaliana; Biosynthesis of triglycerols in Brassica napus L.
Nabi Biopharmaceuticals' NicVAX is potentially advantageous in three important and commercially strategic ways: The vaccine appears to be very well tolerated, even at 200 mcg, the highest dose level tested, allowing us to explore higher and potentially even more efficacious doses; our unique and proprietary mechanism of action for NicVAX, using the same carrier protein as we use in StaphVAX, is based on an established mechanism of action; and, we believe NicVAX is the most advanced smoking cessation product of its kind in development.