in previous studies we found that ER[alpha] and ER[beta] had opposing actions in cardiac myocytes
(ER[alpha] rapid signaling had an inhibitory effect, whereas ER[beta] was stimulatory); thus, the rapid actions of BPA in female hearts are mediated by the stimulatory signaling of ER[beta], and the counterbalance of ER[alpha] versus ER[beta] results in the lack of observable response to BPA in male hearts (Belcher et al.
For all other experiments, heart excisions were performed in the morning between 0900 and 1200 hours, and assessments of the cardiac myocytes
were performed during the rest of the business day.
express TLR-4 receptors and are susceptible to direct damage by LPS exposure.
In order to evaluate the effects of R(+)-puIegone on the electrical properties of cardiac myocytes
, we first studied its effect on the action potential waveform of isolated ventricular myocytes.
Cyclic GMP signaling and regulation of SERCA activity during cardiac myocyte
2+] buffering and diffusion in artial cardiac Myocytes
with Inhibited Sacroplasmic Reticulum", Biophysical J.
For example, in cardiac myocytes
, ANP is translated from its gene as a 151-amino acid prepropeptide (11).
Klf15, in turn, controls the level of a potassium channel-interacting protein (KChIP2), which affects how potassium flows out of heart muscle cells called cardiac myocytes
Examples include the use of thermoresponsive polymer-grafted surfaces - such as poly(N-isopropylacrylamide) - for the generation of cell sheets made of cardiac myocytes
, hepatocytes, or periodontal ligament cells
ARVC first described in 1982, is a genetically determined disorder of cardiac myocytes
in which RV myocardium is replaced with fibro-fatty tissue.
Their topics include the delivery of nanosensors to measure the intracellular environment, the cytoplasm diffusion of dendrimers and dendriplexes, the subcellular fate of nanodelivery systems, endolysosomolytically active pH-sensitive polymeric nanotechnology, the potential of photochemical internalization for the cytosolic delivery of nanomedicines, the subcellular targeting of virus-envelope-coated nanoparticles, therapeutic nano-object delivery to subdomains of cardiac myocytes
, and quantum dot labeling to assess the intracellular trafficking of therapeutically active molecules.
We read the outstanding article by Miller and Tazelaar1 recently published in the Archives of Pathology & Laboratory Medicine about the main features of 5 cardiovascular pseudoneoplasms (inflammatory myofibroblastic tumor, hamartoma of mature cardiac myocytes
, mesothelial monocytic cardiac excrescences, calcified amorphous tumor, and lipomatous hypertrophy of the atrial septum).
The significance of free long-chain polyunsaturated fatty acids on membrane electrical excitability in cardiac myocytes
of neonatal rats has been reported .
The myocardium is the main component consisting of cardiac muscle tissue, which is composed of cardiac myocytes
, blood vessels, and connective tissue.
BNP is generally released by cardiac myocytes
in response to ventricular strain (14).