Additional characterization of SINV-3 has revealed that it produces its capsid proteins
from a subgenomic RNA via a frameshifting mechanism (Valles et al.
ORF1 encodes a polyprotein that is cleaved by the virus-encoded protease to produce several nonstructural proteins, including the RNA-dependent RNA polymerase; ORF2 encodes a major capsid protein
, VP1; and ORF3 encodes a small basic protein (VP2) that has been associated with the stability of the capsid (4,5).
Parvovirus B19 capsid protein
VP1 and VP2 immunohistochemistry was negative.
Expression of human papillomavirus type 6 and type 16 capsid proteins
in bacteria and their antigenic characterization.
Because ozone mainly causes capsid protein
damage, viruses with different capsid protein
architecture were assessed.
Those targeting the major viral capsid protein
L1 are markers of infection, and those targeting the viral oncoproteins E6 and E7 are markers for HPV-associated cancer (5, 6).
This work applies the information from tiling theory about the types and locations of bonds expected between capsid proteins
Summers has determined the three-dimensional structure of the capsid protein
and identified molecules that prevent capsid maturation.
AAV naturally exists as several different serotypes, which differ physically in the composition of their capsid proteins
and genome structures.
Functional role of structural disorder in capsid proteins
Objective: The capsid proteins
of viruses have been shown to organize around a variety of non-biological polyanions, in a similar way that proteins assemble around RNA genomes, to form virus-like particles (VLPs).
N-terminal analysis has revealed the margins of the capsid proteins
and the corresponding scissile bonds within the structural polyprotein (Valles and Hashimoto 2008).
, and particularly the interfaces or seams where one connects to another, are very important for assembling and disassembling the HIV coat, said senior author Angela Gronenborn, Ph.
This may be because the viral capsid proteins
are only expressed in the uppermost layers of the HPV-infected epithelium and are not efficiently presented to the systemic immune system.
This intertwining apparently occurs right before the capsid proteins
form into rings.