By further impairing the discharge, the cysts, Brunner gland hyperplasia, and the reactive spindle cell proliferation may cause the extension of the intraduodenal pancreatitis to the groove region, to the dorsocranial pancreas with compression of the duct of Wirsung, thus adding an obstructive component to the damaging effect of alcohol for the development of the paraduodenal pancreatitis.
The pseudotumoral presentation is the product of a fibroinflammatory process within the intraduodenal pancreatic parenchyma associated with cystic transformation, myoid stromal proliferation, and Brunner gland hyperplasia.
There were also hyperplastic lobules of Brunner gland, lined by cylindrical clear mucinous cells with basal hyperchromatic nuclei (Figures 1 and 2).
Despite the presence of prominent mature adipose tissue, our lesion can be distinguished from a duodenal lipoma by the presence of ectopic Brunner gland and dilated ducts.
Brunner gland hamartoma is a benign lesion, which can be treated by limited surgical resection or polypectomy.