Sir Adrian Cadbury, Sir Dominic Cadbury and Prof Jo Bradwell at the Binding Site
after it won a Queen's Award in 2007
Analysis of the physical association of CD59 with components of the MAC indicated C8[alpha] contains a binding site
for CD59 (18).
The E-VAC is a synthetic portion of gp120 that successfully mimics the shape of the CD4 binding site
expressed by the HIV virus.
is also active in the fields of autoimmune and infectious diseases, with a wide range of assays across different technologies.
The CoA binding site
is located at the interface of all three domains.
Prof Bradwell, 68, remains a professor at Birmingham University where the Binding Site
leases laboratories and does much of its research.
Franks, PhD, professor of biophysics and anaesthetics, the group has spent years creating a photoanalogue of propofol that both behaves in precisely the same way as propofol and contains a labeling group that permanently attaches to its binding site
on the GAB receptor when exposed to a specific wavelength of light.
Prof Jo Bradwell, founder of The Binding Site
and a Professor at Birmingham University, received the latest accolade from the Lord Lieutenant of the West Midlands, Paul Sabapathy.
This is an exciting period for The Binding Site
as our leading product Freelite(TM) continues to develop its international footprint and we continue to work on developing new products and entering new markets.
In 2007 Binding Site
introduced its own turbidimetric bench top analyser, the SPAPLUS which is optimised for running Freelite(TM) and other high sensitivity tests, allowing access to the test across all clinical laboratories.
This result indicated that the common binding site
was a nonclassical membrane estrogen receptor.
Cocaine binds to DAT and abolishes its transport activity, but the localization of the drug binding site
and its relationship to the dopamine translocation pathway still remain unclear.
Results confirmed that C8[gamma] has a distinct binding site
for an unidentified small, lipophilic molecule.
Furthermore, the regions of the protein that undergo the conformational change contain the binding site
for RNA polymerase, which plays a crucial role in the early stages of protein synthesis.
Given a small number of competitive ligands for a protein binding site
, this method can also produce an optimal superposition, maximizing pairwise similarities while minimizing total volume.