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Survival is also related to tumor location: patients with distal bile duct carcinomas do better than patients with mid, proximal, or gallbladder tumors (2).
Because 5% of patients with bile duct carcinoma have synchronous carcinomas of the gallbladder, examination of the entire surgical specimen, including the gallbladder, is advised.
Well-differentiated adenocarcinoma, gastric foveolar type, of the extrahepatic bile ducts: a previously unrecognized and distinctive morphologic variant of bile duct carcinoma.
In most cases the focal type involves the head of the pancreas and strikingly resembles pancreatic or terminal bile duct carcinoma.
5,15-17) In the literature, MUC4 overexpression is associated with more aggressiveness and increased metastases in breast cancer, extrahepatic bile duct carcinoma, and cholangiocarcinoma.
Bile duct carcinoma associated with multiple von Meyenburg complexes in the liver.
Many of these, such as pancreatic cancer, breast and ovarian cancers, bile duct carcinomas and tumours of the head and neck, produce too much EpCAM - and this is frequently associated with an extremely poor prognosis of the disease.