Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell
Betatrophin: A Hormone that Controls Pancreatic Beta-Cell
The curcumin group had better functioning of beta-cells
(cells of the pancreas that store and release insulin and C-peptide), decreased insulin resistance and higher adiponectin levels compared to the placebo group.
loss, where apoptosis occurs without compensatory regeneration, has been demonstrated in T2DM.
Nasdaq: AMLN) and Eli Lilly and Company (NYSE: LLY) today announced results from a study comparing the effect of long-term treatment with either BYETTA (exenatide) injection or Lantus (insulin glargine) on overall beta-cell
mTOT Modulators may provide a new tool for preserving beta-cell
function in patients with type 2 diabetes
Not only did those taking the DDP-4 blocker maintain control over their blood sugar concentrations, they also showed signs of improved beta-cell
function in the pancreas.
The objective of the type 1 diabetes stem cell technology platform is to develop, characterize and produce pancreatic islet-like cells as products for beta-cell
hereafter, NGM) announced today that they have entered into a research collaboration and license agreement to discover and develop novel therapeutics that modulate beta-cell
regeneration for the treatment of diabetes.
and his colleagues found signs of beta-cell
depletion in both people with the disease and those with a condition known as impaired glucose tolerance, which often leads to it.
The consortium's goal is to identify molecules that can be used as radiotracers for PET or SPECT imaging and potential quantification of the pancreatic Beta-cell
It is generally understood that inflammation plays a vital role in beta-cell
Some of these patients, however, probably have autoimmune beta-cell
destruction, Elias says, making p277 a possible treatment for them, too.
Indeed, Eisenbarth and other researchers are giving insulin or its derivatives to children at genetic risk of type 1 diabetes in hopes of inoculating them against beta-cell
This study represents the first use of DNA chips to study islets of diabetic patients and the first demonstration of an important role for ARNT and altered gene expression in impaired beta-cell
function in the pathogenesis of human type 2 diabetes," Dr.