beta-lactamase

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  • noun

Synonyms for beta-lactamase

enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic

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References in periodicals archive ?
Prevalence of extended spectrum beta lactamase and AmpC beta lactamase producers among Escherichia coli isolates in a tertiary care hospital in Jaipur.
For amplification of beta lactamases we used two sets of primers for TEM and SHV genes.
Becton Dickinson is an internationally recognized manufacturer and distributor of medical products, including microbiology products for use in hospital and clinical reference laboratories, and is a leader in sales of technology for the rapid detection of the beta lactamase enzyme.
Based on OXIS' proprietary compound, cefesone, Beta-L RED Discs detect the production of the beta lactamase enzyme by certain antibiotic-resistant bacteria that cause infections.
Extended spectrum beta lactamases (ESBLs) are plasmid mediated enzymes that confer resistance to oxyimino-[beta]-lactam antibiotics (1).
Iain Buchanan, Chief Executive Officer of Novexel said "Novexel is very pleased to conclude this transaction with Forest Laboratories which will combine the potent beta lactamase inhibition of NXL 104 with the antibacterial spectrum of ceftaroline.
There are no recommended guidelines for detection of this resistance mechanism and there is a need to address this issue as much as the detection of extended spectrum beta lactamases (ESBLs) since both may co-exist and mask each other.
Metallo beta lactamase (MBL) belongs to a group [beta]-1actamase which requires divalent cations of zinc as cofactors for enzyme activity.
The various mechanisms of drug resistance in Gram-negative bacilli include extended spectrum beta lactamase (ESBL) production (3), AmpC lactamase production (4), effiux mechanisms (5) and porin deficiency (6).
Transferable resistance to third-generation cephalosporins in clinical isolates of Klebsiella pneumoniae: identification of CTX-1, a novel beta lactamase.
Detection and clinical significance of extended-spectrum beta lactamases in a tertiary-care medical center J Clin Microbiol 1997; 35: 206-7.
This property makes beta lactamases an important tool in the manufacture of beta-lactam antibiotics, where they are used for sterility testing of bulk products.
Extended spectrum beta lactamases (ESBLs) are Ambler class A [beta]-lactamase enzymes that have the ability to hydrolyze [beta]-lactam antibiotics containing an oxyimino group (third generation cephalosporins and aztreonam) and are inhibited by [beta]-1actamase inhibitors (1).
The production of beta lactamases is one of the most important mechanisms of resistance.