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Association of alveolar rhabdomyosarcoma with Beckwith-Wiedemann syndrome.
Allelic methylation of H19 and IGF2 in the Beckwith-Wiedemann syndrome.
But 1,000 is too few to reveal increases in anomalies such as Beckwith-Wiedemann syndrome, which normally occurs in only one in 15,000 births.
Diseases that cause enlargement of the tongue from multiple lesions include Down syndrome and rare conditions such as hypothyroidism, Beckwith-Wiedemann syndrome, the mucopolysaccharidoses (MPS), multiple endocrine neoplasia syndrome type 2B (MEN 2B) and neurofibromatosis (von Recklinghausen's disease of the skin).
Among the unexplained, inherited abnormalities that Engel mentions as candidates are Beckwith-Wiedemann syndrome, Miller-Dieker syndrome and Silver-Russell syndrome.
Beckwith-Wiedemann Syndrome and Hemihyperplasia (Rosanna Weksberg, Cheryl Shuman, and Bruce Beckwith).
1) There are several syndromes associated with hepatoblastoma, including familial adenomatous polyposis, Beckwith-Wiedemann syndrome, and trisomy 18.
Six had Beckwith-Wiedemann syndrome, when only one would normally be expected in such a sample size.
Beckwith-Wiedemann syndrome (BWS) is a clinically and genetically heterogeneous disorder characterized by macrosomia, macroglossia, hemihypertrophy, transverse creases of the ear lobes, hypoglycemia, and predisposition to childhood tumors.
2 fold increase in malignant tumour of the retina; 5% incidence of Beckwith-Wiedemann Syndrome (large tongue, predisposition to cancer); in Brazil, the incidence of cancer increased 117 times; cerebral palsy increased 1.