The distance from the tip of this handle to the edge of the blade is about the length of 25 base pairs
, the team reports in the Jan.
Differences in the evolutionary duplication of complete or partial genes, not of individual base pairs
, primarily distinguish chimp DNA from that of people, report Washington's Evan E.
As chemical reactions occur in each well, they yield flashes of light signifying which base pairs
are located along the segment.
The enzyme that the Scripps group created replicates DNA containing the fifth base with relatively high fidelity--only one mistake for every 1,000 base pairs
This is no simple task because even using current advanced capillary-based DNA sequencers, it still costs over $10 million to sequence three billion base pairs
, according to the March 1 issue of GEN.
To construct the sequence, which consists of 5,386 DNA building blocks, or base pairs
, strung into a single chromosome, J.
The company's purification products and services are based on the proven and patented Solid Phase Reversible Immobilization (SPRI(TM)) technology, which has been used to sequence over 20 billion base pairs
of high-quality DNA or more than one-third of the human genome.
The team's analyses suggest that as many as 4,000 fragments of nuclear DNA measuring at least 100 base pairs
in length may be present in each gram of the animal's desiccated feces.
The company's purification products and services are based on the proven and patented Solid Phase Reversible Immobilization (SPRI(TM)) technology, which has been adopted by several of the largest genome research facilities, resulting in more base pairs
contributed to GenBank than any other nucleic acid purification technology and used to sequence over one-third of the human genome.
The human genome sequence alone comprises some 3 billion base pairs
This "universal cutter" will support the reliable assembly of DNA fragments of 100,000 base pairs
or larger and allow Blue Heron Bio to extend its GeneMaker(R) gene synthesis service to include large genomic DNA fragments and bacterial genomes.
9 billion base pairs
that make up the human genetic code, according to Lander, Waterston, and their dozens of colleagues.
Agencourt scientists contributed to the BAC based sequencing effort on the genome sequence of human chromosome 10, the finished sequence of which comprises a total of 131,666,441 base pairs
represented by 1,357 annotated genes.
When an RNA strand folds upon itself, base pairs
near each other link up to create loops, twists, and kinks, features known as RNA's secondary structure.
4 million base pairs
, the protein-encoding sub-units of DNA.