Furthermore, a relatively prominent basal cell layer
with visible nucleoli may be present in central zone glands, which may be mistaken for the nucleoli seen in HGPIN.
The basal cell layer
has cuboidal cells which lack rete ridges, the cyst lining has buddings and is much folded.
Combination of AMACR and basal cell marker, either p63/HMWCK has the advantage of highlighting the presence of malignant cells and absence of basal cell layer
According to p63 immunostaining, the positivity of basal cell layer
in BPH and PAC cases were seen in 92% and 4% of cases, respectively.
On the other hand, the basal cell layer
shows good positivity (Figures 1 and 2).
The basal cell layer
is the lowest layer of the epidermis.
9) Ki-67 positive cells were mostly detected in the suprabasal cell layer than the basal cell layer
Histopathology (Figures 4 and 5) of the papular, polygonal lesion showed compact orthokeratosis, wedge-shaped hypergranulosis, irregular acanthosis, vacuolar degeneration of basal cell layer
and band-like upper dermal lymphocytic infiltrate.
Keratin distribution in epithelia K5/14 Basal cell layer
of both the keratinized and non-keratinized stratified epithelium K1/10 Keratinized epidermis K6/16 Spinous cell layer of keratinized mucosa K4/13 Intermediate layer of non-keratinized epithelium K19 Basal layer of non-keratinized epithelium K9 Suprabasal cells of palmar and plantar epidermis Keratin expression in gingival K5/14 Basal cell layer
K19 Basal cell layer
ofjunctional epithelium and gingival margin K8, 18, 13, 16, 19 Superficial layers ofjunctional epithelium K4, 13, 16 Superficial layer of gingival margin K1/10, K6/16 and Superficial layers of outer gingival K2p epithelium Distribution of keratin in the dorsal aspect of the tongue (Dale et al 1990).
BCC usually originate from basal cell layer
or outer root sheath of hair follicles and it is considered as an adnexal tumor in WHO classification.
Also, the staining was restricted to the basal cell layer
in non-dysplastic leukoplakias, with an increase in suprabasal positivity as the grade of dysplasia increased.
1c) and S100, and PCNA were 1+ in the basal cell layer
This intraglandular proliferation is consistently surrounded by a basal cell layer
that is often attenuated and disrupted, especially in high-grade PIN.
The epidermis has four layers: the stratum corneum, the granular layer, the squamous cell layer and the basal cell layer
Genomics of Epidermolysis Bullosa EB Type Level of Blistering Genes Simplex Basal cell layer
KRT5, KRT14 Hemidesmosomal Basal cell/lamina BPAG2, ITGB4, ITGA6 lucida interface (PLEC1 with muscular dystrophy) Junctional Lamina lucida LAMA3, LAMB3, LAMC2 Dystrophic Sublamina densa COL7A1 Source: Dr.