WASHINGTON -- Clinical genetic testing for the BRCA1 and BRCA2 genes
allows physicians to more precisely identify who is at high risk for certain cancers, Dr.
uk Faulty gene that causes breast cancer A FAULTY copy of the BRCA2 gene
causes hundreds of UK cases of breast cancer in women every year, and can be passed on to both sexes through the generations.
The finding of the BRCA2 gene
means that there is a greater chance that your husband's cancer will be aggressive and therefore his treatment has to become more radical.
Use of oral contraceptives may not protect against ovarian cancer in women with a mutation in the BRCA1 or BRCA2 gene
, said Dr.
A new computer model devised at the Dana-Farber Cancer Institute and Harvard Medical School, both in Boston, now suggests that a woman carrying a mutated BRCA1 or BRCA2 gene
could add 2.
Oncormed, which recently received a worldwide, exclusive license to the BRCA2 gene
for diagnostic purposes, will actively seek corporate and institutional partners to develop and market diagnostic technologies and products and to perform diagnostic services utilizing BRCA1 and BRCA2.
After ruling out the BRCA2 gene
, we found that FRY, a gene immediately adjacent to the rat BRCA2 suppressor gene, was mutated in the susceptible F344 strain," said Dr.
The study involved data from 321 families with the faulty BRCA2 gene
living in and around Manchester and Birmingham.
The chance of radiation-induced breast cancer may outweigh the benefits of mammograms for women under 30 with the BRCA1 or BRCA2 gene
, according to the study.
Prophylactic mastectomy reduced the incidence of breast cancer in women with a mutation of the BRCA1 or BRCA2 gene
, said Dr.
The researchers suspect, however, that the entire BRCA2 gene
could include as many as 12,000 base pairs.
An estimated five percent to 10 percent of female breast cancers are due to inherited gene mutations, with BRCA1 and BRCA2 gene
mutations the most commonly identified cause.
One of the things we know, for instance, is that in the under-55 age group approximately one in 50 men has a mutation in the BRCA2 gene
, which is also linked to breast cancer and raises the risk of prostate cancer.
But in this situation, the women all had an inherited mutation in either the BRCA1 or BRCA2 gene
and we could exploit that weakness in the tumour.
And after several bouts of radiotherapy and chemotherapy, she was later diagnosed with the BRCA2 gene
which gives her nine-year-old daughter, Jessica, a 50% chance of contracting breast cancer.