as cause of haemorrhagic cystitis after bone marrow transplantation.
A prospective Longitudinal study of BK virus
infection in 104 renal transplant recipients.
Both viruses have been shown to be excreted in the urine of immunocompromised individuals, but BK virus
is excreted more often than JC virus.
has tropism for human salivary gland cells in vitro: implications for transmission.
This finding may be related to the antiviral effect of CMX001 against BK virus
(BKV) and John Cunningham virus (JCV), for example, are ubiquitous human polyomavirus infections.
Designed to help laboratories assess the performance of molecular diagnostic test procedures for BK virus
, this panel plays an important role in the management of transplant patients by assisting laboratories in providing quality diagnostic results.
Chimerix's presentations on CMX001 address the emerging safety profile of the compound and early clinical data on its activity against BK virus
, and will be presented on Saturday, February 16 from 7:00 am to 5:00 pm MT:
WU polyomavirus (WUPyV) (1) and K1 polyomavirus (KIPyV) (2) are newly described human polyomaviruses most closely related to JC virus (JCV) and BK virus
The company also has conducted studies involving adenovirus, Epstein-Barr virus, cytomegalovirus and BK virus
Unmet Medical and Economic Needs It is widely accepted that viral infections, including CMV, adenovirus (AdV) and BK virus
(BKV) infections, cause significant morbidity and mortality in HSCT recipients.
To the Editor: Before 2007, two human polyomaviruses were known to infect humans: BK virus
and JC virus (1,2).
In addition to CMV, the company offers tests for BK Virus
(BKV), JC Virus (JCV), Epstein-Barr Virus (EBV), and enterovirus.
The poster presentation, entitled "CMX001, a Novel Broad Spectrum Antiviral, May Mitigate Signs of BK Virus
(BKV) Associated Bladder and Kidney End-Organ Damage," is part of the Late Breaking Abstracts session on Monday, July 16th from 12:15-13:30 pm in the Stockholm room.
Monitoring of BK virus
replication in the first year following renal transplantation.