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  • noun

Words related to autoantibody

an antibody acting against tissues of the organism that produces it

References in periodicals archive ?
have autoantibodies, with antinuclear antibody the most prevalent and common type of antibodies present among women, older individuals, and African-Americans.
Rheumatoid factor (RF) autoantibodies, for example, are present in 75 percent of RA patients and three percent to five percent of healthy individuals; 98 percent of SLE patients are positive for antinuclear antibodies (ANAs), but so are up to 15 percent of the general population, especially in higher ages.
4,5) In pursuit of a better test for nephritogenic autoantibodies, Gilkeson and coworkers have developed an assay that detects IgG specific for determinants in DNAse-treated glomerular extracts.
A major consideration includes binding and neutralization of pathogenic autoantibodies to prevent interaction with the autoantigen.
As mentioned, the complement cascade activates autoantibodies and chemotactic factors, which leads to cell degranulation.
Having more types of these autoantibodies is a sign of greater risk; having three imparts an 80 to 90 percent likelihood of getting type I diabetes.
However, the autoantibodies associated with each disease might not be directly involved in pathogenesis and might result from the release of self-antigens that follows tissue destruction.
At a recent American Society of Clinical Oncology (ASCO) meeting, additional evidence was presented showing that the new test system using a panel of six cancer antigens (p53, NY-ES0-1, CAGE, GBU4-5, Annexin 1, and SOX2), when run on an ELISA platform, was able to detect autoantibodies, or "immuno-biomarkers," to lung cancer.
BOSTON -- Successful pregnancies in women with systemic lupus erythematosus depend on a combination of factors, including disease activity at the time of conception, maternal renal function, the presence of lupus-related autoantibodies, and medication use, according to Dr.
Upon reexamination 2-3 months after disease induction, autoantibodies characteristic of chronic GVHD were found to have become significantly elevated in surviving iHg-treated mice, but no markers characteristic of iHg-associated autoimmunity were seen.
In two experiments comparing C1q-deficient mice to normal mice, the researchers found that deficient mice died earlier and had more autoimmune antibodies, or autoantibodies, than the normal mice.
Athena's tests encompass the areas of neurogenetic diagnostics that assist in the detection of mutations in the genetic code responsible for certain disorders; peripheral neuropathy and paraneoplastic diagnostics that detect the presence of autoantibodies that may attack the nervous system; Alzheimer's disease diagnostics; and neutralizing antibody detection assays used to detect the presence of antibodies to one of the most common therapies for relapsing-remitting multiple sclerosis.
Contract award: supply of reagents autoantibodies by elisa and ifa, along with the lease of laboratory equipment to perform signs, reading and archiving of results
Genalyte's Maverick(TM) System's Multiplexed Panels Can Simultaneously Measure Multiple Autoantibodies Rapidly and Accurately --
Cardiac troponin-specific autoantibodies (cTnAAbs), however, can interfere with the detection of these clinically important biomarkers by cardiac troponin I (cTnI) assays designed according to the IFCC-recommended midfragment approach used in clinical practice (2-4).