The study suggests that carbohydrate cravings may be a key and independent marker of atypical depression
and might predict how patients will respond to chromium picolinate therapy," added Docherty.
Anxiety disorders, particularly generalized social anxiety and panic, are more commonly comorbid with atypical depression
than with other depressive subtypes.
We are looking forward to initiating our pilot study of chromium in atypical depression
Other medications that have been cited in studies include cyclobenzaprine for musculoskeletal complaints, monoamine oxidase inhibitors for patients with atypical depression
and over-the-counter analgesics such as acetaminophen or ibuprofen for flu-like symptoms and muscle aches (Kantrowitz et al.
Symptoms unique to atypical depression
include increased appetite, oversleeping, a tendency to feel cheered up temporarily in response to positive events, and extreme sensitivity to perceived rejection by others.
Nasdaq: NXXI) - A new double-blind, placebo-controlled clinical trial in 113 patients diagnosed with atypical depression
found that daily supplementation with chromium picolinate had significant anti-depressant effects in a patient sub-group with high levels of carbohydrate cravings.
Monoamine oxidase inhibitors should be considered for the high proportion of patients in whom atypical depression
symptoms predominate, but tricyclic antidepressants "fail dismally compared to SSRIs," he said.
29 /PRNewswire/ -- A randomized, double-blind, placebo-controlled study assessing chromium picolinate supplementation in 113 people with atypical depression
found that a subset of patients who reported the highest levels of carbohydrate cravings demonstrated significantly greater reductions than the placebo group on four items on the Hamilton Depression Rating Scale (HAM-D-29): carbohydrate craving, appetite increase, increased eating, and diurnal variation of feeling (mood variation throughout the day).
Research: A double-blind, placebo-controlled trial was conducted on 113 subjects to examine the effects of chromium picolinate supplementation on certain symptoms of atypical depression
Forty clinical trials demonstrate the safety and efficacy of Chromax for insulin resistance associated with diabetes, obesity, cardiovascular disease and atypical depression