Adding an atypical antipsychotic
to an antidepressant for treatment-resistant depression is becoming more common, largely to address the high level of unmet need among patients who fail to respond to early-line MDD treatment," said Decision Resources Senior Business Insights Analyst Alana Simorellis, Ph.
There may be some relief on the way for straining state Medicaid budgets, as several major atypical antipsychotics
become available in generic form.
This finding may mean that ziprasidone does not increase cholesterol or triglycerdes, or that the decrease was related to the withdrawal of other atypical antipsychotic
drugs that had initially increased cholesterol and triglycerides.
The study published in the International Journal of Psychiatry in Clinical Practice also found that patients treated with the atypical antipsychotics
quetiapine, risperidone or olanzapine as primary treatment, in addition to adjunctive medications, showed a similar time to efficacy (mean time to efficacy was 11.
Some of the atypical antipsychotics
, like quetiapine, can treat the psychotic symptoms without exacerbating the severity of parkinsonism.
drug therapy for treatment resistant schizophrenia.
longitudinal patient-level claims data, antiepileptic drugs (AEDs), atypical antipsychotics
and selective serotonin reuptake inhibitors capture the largest patient shares among all therapies assessed in newly diagnosed bipolar disorder patients across all three lines of therapy.
New evidence indicates that atypical antipsychotics
are ineffective for eating disorders and substance abuse disorder.
Of those, 5,000 were taking at least one atypical antipsychotic
before the black box warning.
In the latter test, 250 patients with schizophrenia exhibited comparable improvement over 1 year, regardless of whether they had been randomly assigned to receive an atypical antipsychotic
or an older drug.
Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, owing largely to increasing generic competition within the atypical antipsychotic
drug class--starting with Zyprexa's (Eli Lilly) loss of patent protection in the United States and Europe--the bipolar disorder drug market will decline from $6.
14, 2013 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that Dainippon Sumitomo Pharma/Sunovion/Takeda Pharmaceutical's atypical antipsychotic
Latuda will experience significant uptake in the bipolar disorder (BPD) market following the agent's June 2013 U.
Moreover, concomitant therapy with an atypical antipsychotic
agent did not necessarily protect against an increase in anxiety in the 134-patient study.
Perhaps the most prudent clinical approach in this situation is one of careful observation - as opposed to arbitrary discontinuation of a typical or atypical antipsychotic
, which is neither suggested nor implied in the FDA's communication.
Previous trials subsidized by pharmaceutical firms have focused on the particular atypical antipsychotic
drug made by the funder.