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Although atabrine helped maintain American troop strength during the war, American scientists looked for something better, something men would be more likely to take.
The lower their morale, the less hope there was of restoring Atabrine discipline and curbing malaria.
A synthetic substitute, Atabrine, was developed in the US, but an even better drug was made in Germany and when it fell into American hands at the end of the war, the US army copied it and developed the cholorquine compound.
We missionaries took our atabrine and aralen religiously, but the Venezuelans were not so careful.
Clinically approved Atabrine (quinacrine) became the drug of choice in 1943, and, shortly after the war, chloroquine was identified, which has had an enduring influence on antimalarial chemotherapy.