Key Words: Rheumatoid arthritis, rheumatoid
factor, anticyclic citrullinated peptide antibody, TNF-[alpha] inhibitors, infliximab
Table 1: Coxibs currently on the market Generic Name Originator Any Indication etoricoxib Merck & Co Arthritis, osteo Arthritis, rheumatoid
Pain, musculoskeletal Pain, post-operative Dysmenorrhoea celecoxib Pfizer Arthritis, rheumatoid
Arthritis, osteo Pain, musculoskeletal valdecoxib Pfizer Arthritis, rheumatoid
Arthritis, osteo Pain, musculoskeletal Dysmenorrhoea parecoxib sodium Pfizer Pain, post-operative
Etanercept is already FDA approved for the treatment of psoriatic arthritis, rheumatoid
arthritis, juvenile rheumatoid arthritis, and ankylosing spondylitis.
Like some other forms of arthritis, rheumatoid
arthritis occurs much more frequently in women than in men.
The combined diagnosed populations of patients with Crohn's disease, psoriasis, psoriatic arthritis, rheumatoid
arthritis, systemic lupus erythematosus (SLE), and ulcerative colitis in seven leading pharmaceutical markets (United States, France, Germany, Italy, Spain, United Kingdom, and Japan) will grow from 19 million in 2010 to 20.